• The Contribution of Genetic Variation of Streptococcus Pneumoniae to the Clinical Manifestation of Invasive Pneumococcal Disease.

      Cremers, Amelieke J H; Mobegi, Fredrick M; van der Gaast-de Jongh, Christa; van Weert, Michelle; van Opzeeland, Fred J; Vehkala, Minna; Knol, Mirjam J; Bootsma, Hester J; Välimäki, Niko; Croucher, Nicholas J; Meis, Jacques F; Bentley, Stephen; van Hijum, Sacha A F T; Corander, Jukka; Zomer, Aldert L; Ferwerda, Gerben; de Jonge, Marien I (2018-05-17)
      Different clinical manifestations of invasive pneumococcal disease (IPD) have thus far mainly been explained by patient characteristics. Here we studied the contribution of pneumococcal genetic variation to IPD phenotype.