• Transmissible Mycobacterium tuberculosis Strains Share Genetic Markers and Immune Phenotypes.

      Nebenzahl-Guimaraes, Hanna; van Laarhoven, Arjan; Farhat, Maha R; Koeken, Valerie A C M; Mandemakers, Jornt J; Zomer, Aldert; van Hijum, Sacha A F T; Netea, Mihai G; Murray, Megan; van Crevel, Reinout; van Soolingen, Dick (2017-06-01)
      Successful transmission of tuberculosis depends on the interplay of human behavior, host immune responses, and Mycobacterium tuberculosis virulence factors. Previous studies have been focused on identifying host risk factors associated with increased transmission, but the contribution of specific genetic variations in mycobacterial strains themselves are still unknown.
    • Varicella vaccination elicits a humoral and cellular response in children with rheumatic diseases using immune suppressive treatment.

      Groot, Noortje; Pileggi, Gecilmara; Sandoval, Cleonice B; Grein, Ingrid; Berbers, Guy; Ferriani, Virginia Paes Leme; Wulffraat, Nico; de Roock, Sytze (2017-05-15)
      To assess humoral and cellular responses to live-attenuated varicella zoster virus (VZV) vaccination of patients with juvenile idiopathic arthritis (JIA), juvenile dermatomyositis (JDM) or juvenile scleroderma (JScle) compared to those of healthy controls (HC).