• Do we need to change catheter-related bloodstream infection surveillance in the Netherlands? A qualitative study among infection prevention professionals.

      Verberk, Janneke Dm; van der Kooi, Tjallie Ii; Derde, Lennie Pg; Bonten, Marc Jm; de Greeff, Sabine C; van Mourik, Maaike Sm (2021-08-18)
    • Does a "500 million-year-old hormone" disprove Darwin?

      Hafner, Martin; Korthof, Gert (2006-07-01)
    • Does a better adherence to dietary guidelines reduce mortality risk and environmental impact in the Dutch sub-cohort of the European Prospective Investigation into Cancer and Nutrition?

      Biesbroek, Sander; Verschuren, W M Monique; Boer, Jolanda M A; van de Kamp, Mirjam E; van der Schouw, Yvonne T; Geelen, Anouk; Looman, Moniek; Temme, Elisabeth H M (2017-07)
      Guidelines for a healthy diet aim to decrease the risk of chronic diseases. It is unclear as to what extent a healthy diet is also an environmentally friendly diet. In the Dutch sub-cohort of the European Prospective Investigation into Cancer and Nutrition, the diet was assessed with a 178-item FFQ of 40 011 participants aged 20-70 years between 1993 and 1997. The WHO's Healthy Diet Indicator (HDI), the Dietary Approaches to Stop Hypertension (DASH) score and the Dutch Healthy Diet index 2015 (DHD15-index) were investigated in relation to greenhouse gas (GHG) emissions, land use and all-cause mortality risk. GHG emissions were associated with HDI scores (-3·7 % per sd increase (95 % CI -3·4, -4·0) for men and -1·9 % (95 % CI -0·4, -3·4) for women), with DASH scores in women only (1·1 % per sd increase, 95 % CI 0·9, 1·3) and with DHD15-index scores (-2·5 % per sd increase (95 % CI -2·2, -2·8) for men and -2·0 % (95 % CI -1·9, -2·2) for women). For all indices, higher scores were associated with less land use (ranging from -1·3 to -3·1 %). Mortality risk decreased with increasing scores for all indices. Per sd increase of the indices, hazard ratios for mortality ranged from 0·88 (95 % CI 0·82, 0·95) to 0·96 (95 % CI 0·92, 0·99). Our results showed that adhering to the WHO and Dutch dietary guidelines will lower the risk of all-cause mortality and moderately lower the environmental impact. The DASH diet was associated with lower mortality and land use, but because of high dairy product consumption in the Netherlands it was also associated with higher GHG emissions.
    • Does an in-house internist at a GP practice result in reduced referrals to hospital-based specialist care?

      Quanjel, Tessa C C; Winkens, Anne; Spreeuwenberg, Marieke D; Struijs, Jeroen N; Winkens, Ron A G; Baan, Caroline A; Ruwaard, Dirk (2018-01-28)
      Consistent evidence on the effects of specialist services in the primary care setting is lacking. Therefore, this study evaluated the effects of an in-house internist at a GP practice on the number of referrals to specialist care in the hospital setting. Additionally, the involved GPs and internist were asked to share their experiences with the intervention.
    • Does biological rhythm transmit from plants to rhizosphere microbes?

      Lu, Tao; Zhang, Zhenyan; Li, Yan; Zhang, Qi; Cui, Hengzheng; Sun, Liwei; Peijnenburg, W J G M; Peñuelas, Josep; Zhu, Lizhong; Zhu, Yong-Guan; et al. (2021-10-17)
    • Does breast milk adiponectin affect BMI and cardio-metabolic markers in childhood?

      van Rossem, Lenie; Smit, Henriette A; Lentjes, Eef Gwm; Maitimu-Smeele, Inge; Brunekreef, Bert; Koppelman, Gerard H; Wijga, Alet H (2019-02-07)
    • Does early onset asthma increase childhood obesity risk? A pooled analysis of 16 European cohorts.

      Contreras, Zuelma A; Chen, Zhanghua; Roumeliotaki, Theano; Annesi-Maesano, Isabella; Baïz, Nour; von Berg, Andrea; Bergström, Anna; Crozier, Sarah; Duijts, Liesbeth; Ekström, Sandra; et al. (2018-09)
      The parallel epidemics of childhood asthma and obesity over the past few decades have spurred research into obesity as a risk factor for asthma. However, little is known regarding the role of asthma in obesity incidence. We examined whether early-onset asthma and related phenotypes are associated with the risk of developing obesity in childhood.This study includes 21 130 children born from 1990 to 2008 in Denmark, France, Germany, Greece, Italy, The Netherlands, Spain, Sweden and the UK. We followed non-obese children at 3-4 years of age for incident obesity up to 8 years of age. Physician-diagnosed asthma, wheezing and allergic rhinitis were assessed up to 3-4 years of age.Children with physician-diagnosed asthma had a higher risk for incident obesity than those without asthma (adjusted hazard ratio (aHR) 1.66, 95% CI 1.18-2.33). Children with active asthma (wheeze in the last 12 months and physician-diagnosed asthma) exhibited a higher risk for obesity (aHR 1.98, 95% CI 1.31-3.00) than those without wheeze and asthma. Persistent wheezing was associated with increased risk for incident obesity compared to never wheezers (aHR 1.51, 95% CI 1.08-2.09).Early-onset asthma and wheezing may contribute to an increased risk of developing obesity in later childhood.
    • Does GRADE gently close the door on sharing decisions with patients?

      Schoemaker, Casper G; van der Heijden, Geert Jmg (2018-06-20)
    • Does intranasal instillation TiO2cause pulmonary tumorigenesis in male mice?

      Møller, Peter; Wallin, Håkan; Cassee, Flemming R; Loft, Steffen (2017-10-21)
    • Does REACH provide sufficient information to regulate mutagenic and carcinogenic substances?

      Woutersen, Marjolijn; Beekman, Martijn; Pronk, Marja E. J.; Muller, Andre; de Knecht, Joop A.; Hakkert, Betty C.; National Instituut for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, The Netherlands; National Instituut for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, The Netherlands; National Instituut for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, The Netherlands; National Instituut for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, The Netherlands; et al. (2018-08)
    • Does selective migration bias the health impact assessment of urban regeneration programmes in cross-sectional studies? Findings from a Dutch case study.

      Ruijsbroek, Annemarie; Wong, Albert; van den Brink, Carolien; Droomers, Mariël; van Oers, Hans A M; Stronks, Karien; Kunst, Anton E (2019-01-01)
      We examined if the assessment of the health impact of a national Dutch regeneration programme depends on using either a repeated cross-sectional or longitudinal study design. This is important as only the latter design can incorporate migration patterns. For both designs, we compared trends in medication use between target and control districts. We found differences in medication use trends to be modest under the longitudinal design, and not demonstrable under the repeated cross-sectional design. The observed differences were hardly influenced by migration patterns. We conclude that in the Netherlands migration patterns had little effect on the health impact assessment of this national urban regeneration programme, so either the cross-sectional or longitudinal evaluation study design will do.
    • Does surrounding greenness moderate the relationship between apparent temperature and physical activity? Findings from the PHENOTYPE project.

      Ho, Janice Y; Zijlema, Wilma L; Triguero-Mas, Margarita; Donaire-Gonzalez, David; Valentín, Antònia; Ballester, Joan; Chan, Emily Y Y; Goggins, William B; Mo, Phoenix K H; Kruize, Hanneke; et al. (2021-03-08)
    • Does the Health Impact of Exposure to Neighbourhood Green Space Differ between Population Groups? An Explorative Study in Four European Cities.

      Ruijsbroek, Annemarie; Droomers, Mariël; Kruize, Hanneke; van Kempen, Elise; Gidlow, Christopher J; Hurst, Gemma; Andrusaityte, Sandra; Nieuwenhuijsen, Mark J; Maas, Jolanda; Hardyns, Wim; et al. (2017-06-08)
      It has been suggested that certain residents, such as those with a low socioeconomic status, the elderly, and women, may benefit more from the presence of neighbourhood green space than others. We tested this hypothesis for age, gender, educational level, and employment status in four European cities. Data were collected in Barcelona (Spain; n = 1002), Kaunas (Lithuania; n = 989), Doetinchem (The Netherlands; n = 847), and Stoke-on-Trent (UK; n = 933) as part of the EU-funded PHENOTYPE project. Surveys were used to measure mental and general health, individual characteristics, and perceived neighbourhood green space. Additionally, we used audit data about neighbourhood green space. In Barcelona, there were positive associations between neighbourhood green space and general health among low-educated residents. In the other cities and for the other population groups, there was little evidence that the association between health and neighbourhood green space differed between population groups. Overall, our study does not support the assumption that the elderly, women, and residents who are not employed full-time benefit more from neighbourhood green space than others. Only in the highly urbanised city of Barcelona did the low-educated group benefit from neighbourhood green spaces. Perhaps neighbourhood green spaces are more important for the health of low-educated residents in particularly highly urbanised areas.
    • Dog ownership, the natural outdoor environment and health: a cross-sectional study.

      Zijlema, Wilma L; Christian, Hayley; Triguero-Mas, Margarita; Cirach, Marta; van den Berg, Magdalena; Maas, Jolanda; Gidlow, Christopher J; Kruize, Hanneke; Wendel-Vos, Wanda; Andrušaitytė, Sandra; et al. (2019-05-27)
    • Dominance of M1 clade among Dutch M1 Streptococcus pyogenes.

      Rümke, Lidewij W; de Gier, Brechje; Vestjens, Stefan M T; van der Ende, Arie; van Sorge, Nina M; Vlaminckx, Bart J M; Witteveen, Sandra; van Santen, Marga; Schouls, Leo M; Kuijper, Ed J (2020-01-01)
    • Dominant influenza A(H3N2) and B/Yamagata virus circulation in EU/EEA, 2016/17 and 2017/18 seasons, respectively.

      Adlhoch, Cornelia; Snacken, René; Melidou, Angeliki; Ionescu, Silviu; Penttinen, Pasi (2018-01-01)
    • Domino effects between pipelines in pipeline corridors.

      Laheij GMH; Chiaradia B; Driessen F; Droge MG; Rozendal S; Theune CJ; Spoelstra MB (2018-05)