A toxicokinetic model for the carry-over of dioxins and PCBs from feed and soil to eggs.
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Type
ArticleLanguage
en
Metadata
Show full item recordTitle
A toxicokinetic model for the carry-over of dioxins and PCBs from feed and soil to eggs.Publiekssamenvatting
A mathematical model for the kinetics of carry-over of dioxins and dioxin-like PCBs from feed mixed with contaminated oil to eggs has been developed. This model incorporates uptake of the compounds over the gut wall and their subsequent transport by blood, distribution over the body, hepatic metabolism and excretion through egg yolk fat. The model is analysed with respect to the possibility of identifying as yet unknown model parameters by fitting these to the experimental data. The model was fitted to the experimental data on the carry-over from feed to eggs. The calibrated model was applied to calculate the steady-state concentrations in eggs which were compared to European Maximum Residue Levels for dioxins in feed and eggs, showing that these limits do not match. The feed limit of 0.75 ng TEQ/kg should be reduced to about 0.17 ng TEQ/kg in order to guarantee egg levels below the residue limit of 3 pg TEQ/g fat. Experimental results of carry-over from contaminated soil were used to estimate the absorption of dioxin-like compounds from soils as compared to the absorption from feed, resulting in a value around 40 to 60% absorption from soil as compared to around 90% absorption from feed.PMID
16644599ae974a485f413a2113503eed53cd6c53
10.1080/02652030500512045
Scopus Count
Collections
Related articles
- Carry-over of dioxins and PCBs from feed and soil to eggs at low contamination levels-- influence of mycotoxin binders on the carry-over from feed to eggs.
- Authors: Hoogenboom LA, Kan CA, Zeilmaker MJ, Van Eijkeren J, Traag WA
- Issue date: 2006 May
- Toxicokinetic study of dioxins and furans in laying chickens.
- Authors: Pirard C, De Pauw E
- Issue date: 2006 May
- Residues of dioxins and PCBs in fat of growing pigs and broilers fed contaminated feed.
- Authors: Hoogenboom LA, Kan CA, Bovee TF, van der Weg G, Onstenk C, Traag WA
- Issue date: 2004 Oct
- The Belgian PCB/dioxin incident: analysis of the food chain contamination and health risk evaluation.
- Authors: Bernard A, Broeckaert F, De Poorter G, De Cock A, Hermans C, Saegerman C, Houins G
- Issue date: 2002 Jan
- Contamination of free-range chicken eggs with dioxins and dioxin-like polychlorinated biphenyls.
- Authors: Schoeters G, Hoogenboom R
- Issue date: 2006 Oct