Meningococcal serogroup C immunogenicity, antibody persistence and memory B-cells induced by the monovalent meningococcal serogroup C versus quadrivalent meningococcal serogroup ACWY conjugate booster vaccine: A randomized controlled trial.
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Authorsvan Ravenhorst, Mariëtte B
van der Klis, Fiona R M
van Rooijen, Debbie M
Knol, Mirjam J
Stoof, Susanne P
Sanders, Elisabeth A M
Berbers, Guy A M
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TitleMeningococcal serogroup C immunogenicity, antibody persistence and memory B-cells induced by the monovalent meningococcal serogroup C versus quadrivalent meningococcal serogroup ACWY conjugate booster vaccine: A randomized controlled trial.
Published inVaccine 2017, 35(36):4745-52
PubliekssamenvattingAdolescents are considered the key transmitters of meningococci in the population. Meningococcal serogroup C (MenC) antibody levels wane rapidly after MenC conjugate vaccination in young children, leaving adolescents with low antibody levels. In this study, we compared MenC immune responses after booster vaccination in adolescence with either tetanus toxoid conjugated MenC (MenC-TT) or MenACWY (MenACWY-TT) vaccine, and aimed to establish an optimal age for this booster.
- Adolescent meningococcal serogroup A, W and Y immune responses following immunization with quadrivalent meningococcal A, C, W and Y conjugate vaccine: Optimal age for vaccination.
- Authors: van Ravenhorst MB, van der Klis FRM, van Rooijen DM, Sanders EAM, Berbers GAM
- Issue date: 2017 Aug 24
- Immunogenicity, Safety and Antibody Persistence of a Booster Dose of Quadrivalent Meningococcal ACWY-tetanus Toxoid Conjugate Vaccine Compared with Monovalent Meningococcal Serogroup C Vaccine Administered Four Years After Primary Vaccination Using the Same Vaccines.
- Authors: Vesikari T, Forsten A, Bianco V, Van der Wielen M, Miller JM
- Issue date: 2015 Dec
- Different Dynamics for IgG and IgA Memory B Cells in Adolescents following a Meningococcal Serogroup C Tetanus Toxoid Conjugate Booster Vaccination Nine Years after Priming: A Role for Priming Age?
- Authors: Stoof SP, Buisman AM, van Rooijen DM, Boonacker R, van der Klis FR, Sanders EA, Berbers GA
- Issue date: 2015
- Salivary antibody levels in adolescents in response to a meningococcal serogroup C conjugate booster vaccination nine years after priming: systemically induced local immunity and saliva as potential surveillance tool.
- Authors: Stoof SP, van der Klis FR, van Rooijen DM, Bogaert D, Trzciński K, Sanders EA, Berbers GA
- Issue date: 2015 Jul 31
- Long-term persistence of protective antibodies in Dutch adolescents following a meningococcal serogroup C tetanus booster vaccination.
- Authors: van Ravenhorst MB, Marinovic AB, van der Klis FR, van Rooijen DM, van Maurik M, Stoof SP, Sanders EA, Berbers GA
- Issue date: 2016 Dec 7