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dc.contributor.authorBuelow, Elena
dc.contributor.authorBello González, Teresita D J
dc.contributor.authorFuentes, Susana
dc.contributor.authorde Steenhuijsen Piters, Wouter A A
dc.contributor.authorLahti, Leo
dc.contributor.authorBayjanov, Jumamurat R
dc.contributor.authorMajoor, Eline A M
dc.contributor.authorBraat, Johanna C
dc.contributor.authorvan Mourik, Maaike S M
dc.contributor.authorOostdijk, Evelien A N
dc.contributor.authorWillems, Rob J L
dc.contributor.authorBonten, Marc J M
dc.contributor.authorvan Passel, Mark W J
dc.contributor.authorSmidt, Hauke
dc.contributor.authorvan Schaik, Willem
dc.date.accessioned2018-01-09T12:43:17Z
dc.date.available2018-01-09T12:43:17Z
dc.date.issued2017-08-14
dc.identifier.citationComparative gut microbiota and resistome profiling of intensive care patients receiving selective digestive tract decontamination and healthy subjects. 2017, 5 (1):88 Microbiomeen
dc.identifier.issn2049-2618
dc.identifier.pmid28803549
dc.identifier.doi10.1186/s40168-017-0309-z
dc.identifier.urihttp://hdl.handle.net/10029/621069
dc.description.abstractThe gut microbiota is a reservoir of opportunistic pathogens that can cause life-threatening infections in critically ill patients during their stay in an intensive care unit (ICU). To suppress gut colonization with opportunistic pathogens, a prophylactic antibiotic regimen, termed "selective decontamination of the digestive tract" (SDD), is used in some countries where it improves clinical outcome in ICU patients. Yet, the impact of ICU hospitalization and SDD on the gut microbiota remains largely unknown. Here, we characterize the composition of the gut microbiota and its antimicrobial resistance genes ("the resistome") of ICU patients during SDD and of healthy subjects.
dc.language.isoenen
dc.rightsArchived with thanks to Microbiomeen
dc.titleComparative gut microbiota and resistome profiling of intensive care patients receiving selective digestive tract decontamination and healthy subjects.en
dc.typeArticleen
dc.identifier.journalMicrobiome 2017, 5(1):188en
html.description.abstractThe gut microbiota is a reservoir of opportunistic pathogens that can cause life-threatening infections in critically ill patients during their stay in an intensive care unit (ICU). To suppress gut colonization with opportunistic pathogens, a prophylactic antibiotic regimen, termed "selective decontamination of the digestive tract" (SDD), is used in some countries where it improves clinical outcome in ICU patients. Yet, the impact of ICU hospitalization and SDD on the gut microbiota remains largely unknown. Here, we characterize the composition of the gut microbiota and its antimicrobial resistance genes ("the resistome") of ICU patients during SDD and of healthy subjects.


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