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    Acquisition of wild-type HIV-1 infection in a patient on pre-exposure prophylaxis with high intracellular concentrations of tenofovir diphosphate: a case report.

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    Authors
    Hoornenborg, Elske
    Prins, Maria
    Achterbergh, Roel C A
    Woittiez, Lycke R
    Cornelissen, Marion
    Jurriaans, Suzanne
    Kootstra, Neeltje A
    Anderson, Peter L
    Reiss, Peter
    de Vries, Henry J C
    Prins, Jan M
    de Bree, Godelieve J
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    Type
    Article
    Language
    en
    
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    Title
    Acquisition of wild-type HIV-1 infection in a patient on pre-exposure prophylaxis with high intracellular concentrations of tenofovir diphosphate: a case report.
    Published in
    Lancet HIV 2017, 4(11):e522-e528
    Publiekssamenvatting
    Pre-exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate is highly effective against acquisition of HIV infection, and only two cases of infection with a multidrug-resistant virus have been reported under adequate long-term adherence, as evidenced by tenofovir diphosphate concentrations in dried blood spots. We report a case of wild-type HIV-1 infection despite consistent use of emtricitabine and tenofovir disoproxil fumarate.
    DOI
    10.1016/S2352-3018(17)30132-7
    PMID
    28919303
    URI
    http://hdl.handle.net/10029/621115
    ae974a485f413a2113503eed53cd6c53
    10.1016/S2352-3018(17)30132-7
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