Acquisition of wild-type HIV-1 infection in a patient on pre-exposure prophylaxis with high intracellular concentrations of tenofovir diphosphate: a case report.
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Authors
Hoornenborg, ElskePrins, Maria
Achterbergh, Roel C A
Woittiez, Lycke R
Cornelissen, Marion
Jurriaans, Suzanne
Kootstra, Neeltje A
Anderson, Peter L
Reiss, Peter
de Vries, Henry J C
Prins, Jan M
de Bree, Godelieve J
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ArticleLanguage
en
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Show full item recordTitle
Acquisition of wild-type HIV-1 infection in a patient on pre-exposure prophylaxis with high intracellular concentrations of tenofovir diphosphate: a case report.Published in
Lancet HIV 2017, 4(11):e522-e528Publiekssamenvatting
Pre-exposure prophylaxis (PrEP) with emtricitabine and tenofovir disoproxil fumarate is highly effective against acquisition of HIV infection, and only two cases of infection with a multidrug-resistant virus have been reported under adequate long-term adherence, as evidenced by tenofovir diphosphate concentrations in dried blood spots. We report a case of wild-type HIV-1 infection despite consistent use of emtricitabine and tenofovir disoproxil fumarate.PMID
28919303ae974a485f413a2113503eed53cd6c53
10.1016/S2352-3018(17)30132-7
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