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    Variation in loss of immunity shapes influenza epidemics and the impact of vaccination.

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    Authors
    Woolthuis, Rutger G
    Wallinga, Jacco
    van Boven, Michiel
    Type
    Article
    Language
    en
    
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    Title
    Variation in loss of immunity shapes influenza epidemics and the impact of vaccination.
    Published in
    BMC Infect Dis 2017, 17(1):632
    Publiekssamenvatting
    Protective antibody immunity against the influenza A virus wanes in 2-7 years due to antigenic drift of the virus' surface proteins. The duration of immune protection is highly variable because antigenic evolution of the virus is irregular. Currently, the variable nature of the duration of immunity has had little attention in analyses of the impact of vaccination, including cost-effectiveness studies.
    DOI
    10.1186/s12879-017-2716-y
    PMID
    28927373
    URI
    http://hdl.handle.net/10029/621120
    ae974a485f413a2113503eed53cd6c53
    10.1186/s12879-017-2716-y
    Scopus Count
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