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dc.contributor.authorWoolthuis, Rutger G
dc.contributor.authorWallinga, Jacco
dc.contributor.authorvan Boven, Michiel
dc.date.accessioned2018-01-10T07:50:36Z
dc.date.available2018-01-10T07:50:36Z
dc.date.issued2017-09-19
dc.identifier.citationVariation in loss of immunity shapes influenza epidemics and the impact of vaccination. 2017, 17 (1):632 BMC Infect. Dis.en
dc.identifier.issn1471-2334
dc.identifier.pmid28927373
dc.identifier.doi10.1186/s12879-017-2716-y
dc.identifier.urihttp://hdl.handle.net/10029/621120
dc.description.abstractProtective antibody immunity against the influenza A virus wanes in 2-7 years due to antigenic drift of the virus' surface proteins. The duration of immune protection is highly variable because antigenic evolution of the virus is irregular. Currently, the variable nature of the duration of immunity has had little attention in analyses of the impact of vaccination, including cost-effectiveness studies.
dc.language.isoenen
dc.rightsArchived with thanks to BMC infectious diseasesen
dc.subject.meshChild
dc.subject.meshCost-Benefit Analysis
dc.subject.meshDisease Outbreaks
dc.subject.meshEpidemics
dc.subject.meshHumans
dc.subject.meshInfluenza A virus
dc.subject.meshInfluenza Vaccines
dc.subject.meshInfluenza, Human
dc.subject.meshModels, Theoretical
dc.subject.meshSeasons
dc.subject.meshVaccination
dc.titleVariation in loss of immunity shapes influenza epidemics and the impact of vaccination.en
dc.typeArticleen
dc.identifier.journalBMC Infect Dis 2017, 17(1):632en
refterms.dateFOA2018-12-18T14:02:43Z
html.description.abstractProtective antibody immunity against the influenza A virus wanes in 2-7 years due to antigenic drift of the virus' surface proteins. The duration of immune protection is highly variable because antigenic evolution of the virus is irregular. Currently, the variable nature of the duration of immunity has had little attention in analyses of the impact of vaccination, including cost-effectiveness studies.


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