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dc.contributor.authorChen, Guangchao
dc.contributor.authorPeijnenburg, Willie J G M
dc.contributor.authorXiao, Yinlong
dc.contributor.authorVijver, Martina G
dc.date.accessioned2018-02-06T11:59:15Z
dc.date.available2018-02-06T11:59:15Z
dc.date.issued2017-04-05
dc.identifier.citationDeveloping species sensitivity distributions for metallic nanomaterials considering the characteristics of nanomaterials, experimental conditions, and different types of endpoints. 2017 Food Chem. Toxicol.en
dc.identifier.issn1873-6351
dc.identifier.pmid28390859
dc.identifier.doi10.1016/j.fct.2017.04.003
dc.identifier.urihttp://hdl.handle.net/10029/621295
dc.description.abstractA species sensitivity distribution (SSD) for engineered nanomaterials (ENMs) ranks the tested species according to their sensitivity to a certain ENM. An SSD may be used to estimate the maximum acceptable concentrations of ENMs for the purpose of environmental risk assessment. To construct SSDs for metal-based ENMs, more than 1800 laboratory derived toxicity records of metallic ENMs from >300 publications or open access scientific reports were retrieved. SSDs were developed for the metallic ENMs grouped by surface coating, size, shape, exposure duration, light exposure, and different toxicity endpoints. It was found that PVP- and sodium citrate- coatings enhance the toxicity of Ag ENMs as concluded from the relevant SSDs. For the Ag ENMs with different size ranges, differences in behavior and/or effect were only observed at high exposure concentrations. The SSDs of Ag ENMs separated by both shape and exposure duration were all nearly identical. Crustaceans were found to be the most vulnerable group to metallic ENMs. In spite of the uncertainties of the results caused by limited data quality and availability, the present study provided novel information about building SSDs for distinguished ENMs and contributes to the further development of SSDs for metal-based ENMs.
dc.language.isoenen
dc.rightsArchived with thanks to Food and chemical toxicology : an international journal published for the British Industrial Biological Research Associationen
dc.titleDeveloping species sensitivity distributions for metallic nanomaterials considering the characteristics of nanomaterials, experimental conditions, and different types of endpoints.en
dc.typeArticleen
dc.identifier.journalFood aFood Chem Toxicol 2018; advance online publication (ahead of print)nd chemical toxicology : an international journal published for the British Industrial Biological Research Associationen
html.description.abstractA species sensitivity distribution (SSD) for engineered nanomaterials (ENMs) ranks the tested species according to their sensitivity to a certain ENM. An SSD may be used to estimate the maximum acceptable concentrations of ENMs for the purpose of environmental risk assessment. To construct SSDs for metal-based ENMs, more than 1800 laboratory derived toxicity records of metallic ENMs from >300 publications or open access scientific reports were retrieved. SSDs were developed for the metallic ENMs grouped by surface coating, size, shape, exposure duration, light exposure, and different toxicity endpoints. It was found that PVP- and sodium citrate- coatings enhance the toxicity of Ag ENMs as concluded from the relevant SSDs. For the Ag ENMs with different size ranges, differences in behavior and/or effect were only observed at high exposure concentrations. The SSDs of Ag ENMs separated by both shape and exposure duration were all nearly identical. Crustaceans were found to be the most vulnerable group to metallic ENMs. In spite of the uncertainties of the results caused by limited data quality and availability, the present study provided novel information about building SSDs for distinguished ENMs and contributes to the further development of SSDs for metal-based ENMs.


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