Livestock-associated risk factors for pneumonia in an area of intensive animal farming in the Netherlands.
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Authors
Freidl, Gudrun SSpruijt, Ineke T
Borlée, Floor
Smit, Lidwien A M
van Gageldonk-Lafeber, Arianne B
Heederik, Dick J J
Yzermans, Joris
van Dijk, Christel E
Maassen, Catharina B M
van der Hoek, Wim
Type
ArticleLanguage
en
Metadata
Show full item recordTitle
Livestock-associated risk factors for pneumonia in an area of intensive animal farming in the Netherlands.Published in
Plos One 2017; 12(3)e0174796Publiekssamenvatting
Previous research conducted in 2009 found a significant positive association between pneumonia in humans and living close to goat and poultry farms. However, as this result might have been affected by a large goat-related Q fever epidemic, the aim of the current study was to re-evaluate this association, now that the Q-fever epidemic had ended. In 2014/15, 2,494 adults (aged 20-72 years) living in a livestock-dense area in the Netherlands participated in a medical examination and completed a questionnaire on respiratory health, lifestyle and other items. We retrieved additional information for 2,426/2,494 (97%) participants from electronic medical records (EMR) from general practitioners. The outcome was self-reported, physician-diagnosed pneumonia or pneumonia recorded in the EMR in the previous three years. Livestock license data was used to determine exposure to livestock. We quantified associations between livestock exposures and pneumonia using odds ratios adjusted for participant characteristics and comorbidities (aOR). The three-year cumulative frequency of pneumonia was 186/2,426 (7.7%). Residents within 2,000m of a farm with at least 50 goats had an increased risk of pneumonia, which increased the closer they lived to the farm (2,000m aOR 1.9, 95% CI 1.4-2.6; 500m aOR 4.4, 95% CI 2.0-9.8). We found no significant associations between exposure to other farm animals and pneumonia. However, when conducting sensitivity analyses using pneumonia outcome based on EMR only, we found a weak but statistically significant association with presence of a poultry farm within 1,000m (aOR: 1.7, 95% CI 1.1-2.7). Living close to goat and poultry farms still constitute risk factors for pneumonia. Individuals with pneumonia were not more often seropositive for Coxiella burnetii, indicating that results are not explained by Q fever. We strongly recommend identification of pneumonia causes by the use of molecular diagnostics and investigating the role of non-infectious agents such as particulate matter or endotoxins.PMID
28362816ae974a485f413a2113503eed53cd6c53
10.1371/journal.pone.0174796
Scopus Count
Collections
Related articles
- Associations between pneumonia and residential distance to livestock farms over a five-year period in a large population-based study.
- Authors: Kalkowska DA, Boender GJ, Smit LAM, Baliatsas C, Yzermans J, Heederik DJJ, Hagenaars TJ
- Issue date: 2018
- Remarkable spatial variation in the seroprevalence of Coxiella burnetii after a large Q fever epidemic.
- Authors: Pijnacker R, Reimerink J, Smit LAM, van Gageldonk-Lafeber AB, Zock JP, Borlée F, Yzermans J, Heederik DJJ, Maassen CBM, van der Hoek W
- Issue date: 2017 Nov 21
- Q fever and pneumonia in an area with a high livestock density: a large population-based study.
- Authors: Smit LA, van der Sman-de Beer F, Opstal-van Winden AW, Hooiveld M, Beekhuizen J, Wouters IM, Yzermans J, Heederik D
- Issue date: 2012
- Coxiella burnetii (Q fever) in Rattus norvegicus and Rattus rattus at livestock farms and urban locations in the Netherlands; could Rattus spp. represent reservoirs for (re)introduction?
- Authors: Reusken C, van der Plaats R, Opsteegh M, de Bruin A, Swart A
- Issue date: 2011 Aug 1
- The 2007–2010 Q fever epidemic in The Netherlands: characteristics of notified acute Q fever patients and the association with dairy goat farming.
- Authors: Dijkstra F, van der Hoek W, Wijers N, Schimmer B, Rietveld A, Wijkmans CJ, Vellema P, Schneeberger PM
- Issue date: 2012 Feb