Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis.
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Authors
Ruesen, CarolienChaidir, Lidya
van Laarhoven, Arjan
Dian, Sofiati
Ganiem, Ahmad Rizal
Nebenzahl-Guimaraes, Hanna
Huynen, Martijn A
Alisjahbana, Bachti
Dutilh, Bas E
van Crevel, Reinout
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ArticleLanguage
en
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Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis.Published in
BMC Genomics 2018; 19(1):122Publiekssamenvatting
Meningitis is the most severe manifestation of tuberculosis. It is largely unknown why some people develop pulmonary TB (PTB) and others TB meningitis (TBM); we examined if the genetic background of infecting M. tuberculosis strains may be relevant.PMID
29402222ae974a485f413a2113503eed53cd6c53
10.1186/s12864-018-4498-z
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