Revision of clinical case definitions: influenza-like illness and severe acute respiratory infection.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Mounts, Anthony Wayne
Katz, Mark A
Olivera, Maria Teresa da Costa
Ortiz, Justin R
Yahaya, Ali Ahmed
MetadataShow full item record
TitleRevision of clinical case definitions: influenza-like illness and severe acute respiratory infection.
Published inBull World Health Organ 2018; 96(2):122-8
PubliekssamenvattingThe formulation of accurate clinical case definitions is an integral part of an effective process of public health surveillance. Although such definitions should, ideally, be based on a standardized and fixed collection of defining criteria, they often require revision to reflect new knowledge of the condition involved and improvements in diagnostic testing. Optimal case definitions also need to have a balance of sensitivity and specificity that reflects their intended use. After the 2009-2010 H1N1 influenza pandemic, the World Health Organization (WHO) initiated a technical consultation on global influenza surveillance. This prompted improvements in the sensitivity and specificity of the case definition for influenza - i.e. a respiratory disease that lacks uniquely defining symptomology. The revision process not only modified the definition of influenza-like illness, to include a simplified list of the criteria shown to be most predictive of influenza infection, but also clarified the language used for the definition, to enhance interpretability. To capture severe cases of influenza that required hospitalization, a new case definition was also developed for severe acute respiratory infection in all age groups. The new definitions have been found to capture more cases without compromising specificity. Despite the challenge still posed in the clinical separation of influenza from other respiratory infections, the global use of the new WHO case definitions should help determine global trends in the characteristics and transmission of influenza viruses and the associated disease burden.
- Lessons from a one-year hospital-based surveillance of acute respiratory infections in Berlin- comparing case definitions to monitor influenza.
- Authors: Nachtnebel M, Greutelaers B, Falkenhorst G, Jorgensen P, Dehnert M, Schweiger B, Träder C, Buda S, Eckmanns T, Wichmann O, Hellenbrand W
- Issue date: 2012 Mar 27
- Are we missing respiratory viral infections in infants and children? Comparison of a hospital-based quality management system with standard of care.
- Authors: Alchikh M, Conrad T, Hoppe C, Ma X, Broberg E, Penttinen P, Reiche J, Biere B, Schweiger B, Rath B
- Issue date: 2019 Mar
- Performance of influenza case definitions for influenza community surveillance: based on the French influenza surveillance network GROG, 2009-2014.
- Authors: Casalegno JS, Eibach D, Valette M, Enouf V, Daviaud I, Behillil S, Vabret A, Soulary JC, Benchaib M, Cohen JM, van der Werf S, Mosnier A, Lina B
- Issue date: 2017 Apr 6
- Burden of pediatric influenza A virus infection post swine-flu H1N1 pandemic in Egypt.
- Authors: Khattab A, Shaheen M, Kamel T, El Faramay A, El Rahman SA, Nabil D, Gouda M
- Issue date: 2013 Sep
- Comparison of common acute respiratory infection case definitions for identification of hospitalized influenza cases at a population-based surveillance site in Egypt.
- Authors: Rowlinson E, Peters L, Mansour A, Mansour H, Azazzy N, Said M, Samy S, Abbas E, Abu Elsood H, Fahim M, Eid A, Reaves E, Van Beneden C, Hamid S, Olsen S, Fitzner J, Dueger E
- Issue date: 2021