Impact and cost-effectiveness of different vaccination strategies to reduce the burden of pneumococcal disease among elderly in the Netherlands.

Thorrington, Dominic; van Rossum, Leo; Knol, Mirjam; de Melker, Hester; Rümke, Hans; Hak, Eelko; van Hoek, Albert Jan

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Authors

Thorrington, Dominic
van Rossum, Leo
Knol, Mirjam
de Melker, Hester
Rümke, Hans
Hak, Eelko
van Hoek, Albert Jan

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Article

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Title

Impact and cost-effectiveness of different vaccination strategies to reduce the burden of pneumococcal disease among elderly in the Netherlands.

Published in

Plos One 2018; 13(2):e0192640

Publiekssamenvatting

Streptococcus pneumoniae causes morbidity and mortality among all ages in The Netherlands. To reduce this burden, infants in The Netherlands receive the 10-valent pneumococcal conjugated vaccine (PCV10), but older persons are not targeted. We assessed the impact and cost-effectiveness of vaccination with 23-valent pneumococcal polysaccharide vaccine (PPV23) or 13-valent PCV (PCV13) among all those aged 60, 65 or 70 and/or in combination with replacing PCV10 with PCV13 in the infant vaccination programme.