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    An alternative approach identified optimal risk thresholds for treatment indication: an illustration in coronary heart disease.

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    Authors
    van Giessen, Anoukh
    de Wit, G Ardine
    Moons, Karel G M
    Dorresteijn, Jannick A N
    Koffijberg, Hendrik
    Type
    Article
    Language
    en
    
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    Title
    An alternative approach identified optimal risk thresholds for treatment indication: an illustration in coronary heart disease.
    Published in
    J Clin Epidemiol 2018; 94:122-31
    Publiekssamenvatting
    Treatment thresholds based on risk predictions can be optimized by considering various health (economic) outcomes and performing marginal analyses, but this is rarely performed. We demonstrate a general approach to identify treatment thresholds optimizing individual health (economic) outcomes, illustrated for statin treatment based on 10-year coronary heart disease (CHD) risk predicted by the Framingham risk score.
    DOI
    10.1016/j.jclinepi.2017.09.020
    PMID
    28986242
    URI
    http://hdl.handle.net/10029/621444
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jclinepi.2017.09.020
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