An alternative approach identified optimal risk thresholds for treatment indication: an illustration in coronary heart disease.
dc.contributor.author | van Giessen, Anoukh | |
dc.contributor.author | de Wit, G Ardine | |
dc.contributor.author | Moons, Karel G M | |
dc.contributor.author | Dorresteijn, Jannick A N | |
dc.contributor.author | Koffijberg, Hendrik | |
dc.date.accessioned | 2018-02-22T12:55:01Z | |
dc.date.available | 2018-02-22T12:55:01Z | |
dc.date.issued | 2018-02 | |
dc.identifier.citation | An alternative approach identified optimal risk thresholds for treatment indication: an illustration in coronary heart disease. 2018, 94:122-131 J Clin Epidemiol | en |
dc.identifier.issn | 1878-5921 | |
dc.identifier.pmid | 28986242 | |
dc.identifier.doi | 10.1016/j.jclinepi.2017.09.020 | |
dc.identifier.uri | http://hdl.handle.net/10029/621444 | |
dc.description.abstract | Treatment thresholds based on risk predictions can be optimized by considering various health (economic) outcomes and performing marginal analyses, but this is rarely performed. We demonstrate a general approach to identify treatment thresholds optimizing individual health (economic) outcomes, illustrated for statin treatment based on 10-year coronary heart disease (CHD) risk predicted by the Framingham risk score. | |
dc.language.iso | en | en |
dc.rights | info:eu-repo/semantics/closedAccess | en |
dc.title | An alternative approach identified optimal risk thresholds for treatment indication: an illustration in coronary heart disease. | en |
dc.type | Article | en |
dc.identifier.journal | J Clin Epidemiol 2018; 94:122-31 | en |
html.description.abstract | Treatment thresholds based on risk predictions can be optimized by considering various health (economic) outcomes and performing marginal analyses, but this is rarely performed. We demonstrate a general approach to identify treatment thresholds optimizing individual health (economic) outcomes, illustrated for statin treatment based on 10-year coronary heart disease (CHD) risk predicted by the Framingham risk score. |