Surveillance of circulatingBordetella pertussisstrains in Europe during 1998-2015.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Vermedal Hoegh, Silje
van Gent, Marjolein
Vestrheim, Didrik F
Fry, Norman K
MetadataShow full item record
TitleSurveillance of circulatingBordetella pertussisstrains in Europe during 1998-2015.
Published inJ Clin Microbiol 2018; advance online publication (ahead of print)
PubliekssamenvattingOne reason for increased pertussis incidence is the adaptation of Bordetella pertussis to vaccine-induced immunity by modulating its genomic structure. This study, EUpert IV, includes 265 isolates collected from nine European countries during 2012 to 2015 (n=265) and compares the results to previous EUpert I-III studies (1998-2009). The analyses included genotyping, serotyping and pulsed-field gel electrophoresis (PFGE) and multi-locus variable-number tandem repeat analysis (MLVA). Genotyping results showed only small variation among the common virulence genes ofB. pertussisFrequencies of serotypes Fim2 and Fim3 varied among the four collections. Genomic analyses showed that MLVA type 27 increased to 80% between the periods of 1998-2001 and 2012-2015. Two PFGE profiles, BpSR3 (29.4%) and BpSR10 (27.2%), constituted more than 50% of the circulating isolates in the present collection. Our study indicates that the EuropeanB. pertussispopulation is changing more homogenous after the introduction of acellular pertussis vaccines.
- Multi-locus variable-number tandem repeat analysis of Bordetella pertussis isolates circulating in Poland in the period 1959-2013.
- Authors: Mosiej E, Krysztopa-Grzybowska K, Polak M, Prygiel M, Lutyńska A
- Issue date: 2017 Jun
- Analysis of Bordetella pertussis clinical isolates circulating in European countries during the period 1998-2012.
- Authors: van Gent M, Heuvelman CJ, van der Heide HG, Hallander HO, Advani A, Guiso N, Wirsing von Kőnig CH, Vestrheim DF, Dalby T, Fry NK, Pierard D, Detemmerman L, Zavadilova J, Fabianova K, Logan C, Habington A, Byrne M, Lutyńska A, Mosiej E, Pelaz C, Gröndahl-Yli-Hannuksela K, Barkoff AM, Mertsola J, Economopoulou A, He Q, Mooi FR
- Issue date: 2015 Apr
- Changes in genetic diversity of the Bordetella pertussis population in the United Kingdom between 1920 and 2006 reflect vaccination coverage and emergence of a single dominant clonal type.
- Authors: Litt DJ, Neal SE, Fry NK
- Issue date: 2009 Mar
- Pertactin-deficient Bordetella pertussis isolates in Poland-a country with whole-cell pertussis primary vaccination.
- Authors: Polak M, Zasada AA, Mosiej E, Krysztopa-Grzybowska K, Witkowski L, Rzeczkowska M, Piekarska K, Lutyńska A
- Issue date: 2019 Apr - May
- Pulsed-field gel electrophoresis analysis of Bordetella pertussis isolates circulating in Europe from 1998 to 2009.
- Authors: Advani A, Hallander HO, Dalby T, Krogfelt KA, Guiso N, Njamkepo E, von Könnig CH, Riffelmann M, Mooi FR, Sandven P, Lutynska A, Fry NK, Mertsola J, He Q
- Issue date: 2013 Feb