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    Whole-Genome Next-Generation Sequencing to Study Within-Host Evolution of Norovirus (NoV) Among Immunocompromised Patients With Chronic NoV Infection.

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    Authors
    van Beek, Janko
    de Graaf, Miranda
    Smits, Saskia
    Schapendonk, Claudia M E
    Verjans, Georges M G M
    Vennema, Harry
    van der Eijk, Annemiek A
    Phan, My V T
    Cotten, Matthew
    Koopmans, Marion
    Type
    Article
    Language
    en
    
    Metadata
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    Title
    Whole-Genome Next-Generation Sequencing to Study Within-Host Evolution of Norovirus (NoV) Among Immunocompromised Patients With Chronic NoV Infection.
    Published in
    J Infect Dis 2017; 216(12):1513-24
    Publiekssamenvatting
    The genus Norovirus comprises large genetic diversity, and new GII.4 variants emerge every 2-3 years. It is unknown in which host these new variants originate. Here we study whether prolonged shedders within the immunocompromised population could be a reservoir for newly emerging strains.
    DOI
    10.1093/infdis/jix520
    PMID
    29029115
    URI
    http://hdl.handle.net/10029/621695
    ae974a485f413a2113503eed53cd6c53
    10.1093/infdis/jix520
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