Whole-Genome Next-Generation Sequencing to Study Within-Host Evolution of Norovirus (NoV) Among Immunocompromised Patients With Chronic NoV Infection.
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Authors
van Beek, Jankode Graaf, Miranda
Smits, Saskia
Schapendonk, Claudia M E
Verjans, Georges M G M
Vennema, Harry
van der Eijk, Annemiek A
Phan, My V T
Cotten, Matthew
Koopmans, Marion
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ArticleLanguage
en
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Whole-Genome Next-Generation Sequencing to Study Within-Host Evolution of Norovirus (NoV) Among Immunocompromised Patients With Chronic NoV Infection.Published in
J Infect Dis 2017; 216(12):1513-24Publiekssamenvatting
The genus Norovirus comprises large genetic diversity, and new GII.4 variants emerge every 2-3 years. It is unknown in which host these new variants originate. Here we study whether prolonged shedders within the immunocompromised population could be a reservoir for newly emerging strains.PMID
29029115ae974a485f413a2113503eed53cd6c53
10.1093/infdis/jix520
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