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dc.contributor.authorKoppenaal, H
dc.contributor.authorGroenendijk, F
dc.contributor.authorvan den Berge, M
dc.contributor.authorVerkade, E
dc.contributor.authorVerduin, K
dc.contributor.authorZomer, A L
dc.contributor.authorDuim, B
dc.contributor.authorWagenaar, J A
dc.contributor.authorTijsma, A S L
dc.contributor.authorSpierenburg, M A H
dc.contributor.authorte Wierik, M J M
dc.date.accessioned2018-04-03T12:46:07Z
dc.date.available2018-04-03T12:46:07Z
dc.date.issued2017-10-17
dc.identifier.citation[Outbreak of Campylobacter fetus infection after consumption of unpasteurized sheep's milk cheeses: how to trace the source?] 2017, 161 (0):D1704 Ned Tijdschr Geneeskden
dc.identifier.issn1876-8784
dc.identifier.pmid29057727
dc.identifier.urihttp://hdl.handle.net/10029/621723
dc.description.abstractCampylobacter fetus is a species of gram-negative bacteria whose primary reservoir is the gastrointestinal tracts of cattle and sheep. Human infections are rare, though often invasive and sometimes fatal. In this paper, we studied an outbreak of six patients with a C. fetus infection and outlined their disease histories. In each case we were able to identify factors that led to a reduced resistance, including pre-existing illnesses and old age. Because of the unusually high number of patients that presented in a time period of only five months, the Community Health Services were commissioned to identify the source of infection. Using whole genome sequencing, we showed that 5 out of 6 patients belonged to the same cluster. This One Health approach resulted in the conclusion that the infection originated from unpasteurized sheep's milk processed into unripened cheese. Finally, various measures were put into place to prevent any further outbreaks.
dc.languagedut
dc.language.isonlen
dc.rightsinfo:eu-repo/semantics/closedAccessen
dc.titleEen uitbraak met Campylobacter fetus na het eten van rauwmelkse schapenkaas : Hoe traceer je de bron van een uitbraaknl
dc.typeArticleen
dc.identifier.journalNed Tijdschr Geneeskd 2017; 161(0):D1704en
html.description.abstractCampylobacter fetus is a species of gram-negative bacteria whose primary reservoir is the gastrointestinal tracts of cattle and sheep. Human infections are rare, though often invasive and sometimes fatal. In this paper, we studied an outbreak of six patients with a C. fetus infection and outlined their disease histories. In each case we were able to identify factors that led to a reduced resistance, including pre-existing illnesses and old age. Because of the unusually high number of patients that presented in a time period of only five months, the Community Health Services were commissioned to identify the source of infection. Using whole genome sequencing, we showed that 5 out of 6 patients belonged to the same cluster. This One Health approach resulted in the conclusion that the infection originated from unpasteurized sheep's milk processed into unripened cheese. Finally, various measures were put into place to prevent any further outbreaks.


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