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    Combining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance.

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    Authors
    Brouwer-Brolsma, Elske M
    Brennan, Lorraine
    Drevon, Christian A
    van Kranen, Henk
    Manach, Claudine
    Dragsted, Lars Ove
    Roche, Helen M
    Andres-Lacueva, Cristina
    Bakker, Stephan J L
    Bouwman, Jildau
    Capozzi, Francesco
    De Saeger, Sarah
    Gundersen, Thomas E
    Kolehmainen, Marjukka
    Kulling, Sabine E
    Landberg, Rikard
    Linseisen, Jakob
    Mattivi, Fulvio
    Mensink, Ronald P
    Scaccini, Cristina
    Skurk, Thomas
    Tetens, Inge
    Vergeres, Guy
    Wishart, David S
    Scalbert, Augustin
    Feskens, Edith J M
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    Type
    Article
    Language
    en
    
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    Title
    Combining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance.
    Published in
    Proc Nutr Soc 2017; 76(4):619-27
    Publiekssamenvatting
    FFQ, food diaries and 24 h recall methods represent the most commonly used dietary assessment tools in human studies on nutrition and health, but food intake biomarkers are assumed to provide a more objective reflection of intake. Unfortunately, very few of these biomarkers are sufficiently validated. This review provides an overview of food intake biomarker research and highlights present research efforts of the Joint Programming Initiative 'A Healthy Diet for a Healthy Life' (JPI-HDHL) Food Biomarkers Alliance (FoodBAll). In order to identify novel food intake biomarkers, the focus is on new food metabolomics techniques that allow the quantification of up to thousands of metabolites simultaneously, which may be applied in intervention and observational studies. As biomarkers are often influenced by various other factors than the food under investigation, FoodBAll developed a food intake biomarker quality and validity score aiming to assist the systematic evaluation of novel biomarkers. Moreover, to evaluate the applicability of nutritional biomarkers, studies are presently also focusing on associations between food intake biomarkers and diet-related disease risk. In order to be successful in these metabolomics studies, knowledge about available electronic metabolomics resources is necessary and further developments of these resources are essential. Ultimately, present efforts in this research area aim to advance quality control of traditional dietary assessment methods, advance compliance evaluation in nutritional intervention studies, and increase the significance of observational studies by investigating associations between nutrition and health.
    DOI
    10.1017/S0029665117003949
    PMID
    29137687
    URI
    http://hdl.handle.net/10029/621744
    ae974a485f413a2113503eed53cd6c53
    10.1017/S0029665117003949
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