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dc.contributor.authorBrouwer-Brolsma, Elske M
dc.contributor.authorBrennan, Lorraine
dc.contributor.authorDrevon, Christian A
dc.contributor.authorvan Kranen, Henk
dc.contributor.authorManach, Claudine
dc.contributor.authorDragsted, Lars Ove
dc.contributor.authorRoche, Helen M
dc.contributor.authorAndres-Lacueva, Cristina
dc.contributor.authorBakker, Stephan J L
dc.contributor.authorBouwman, Jildau
dc.contributor.authorCapozzi, Francesco
dc.contributor.authorDe Saeger, Sarah
dc.contributor.authorGundersen, Thomas E
dc.contributor.authorKolehmainen, Marjukka
dc.contributor.authorKulling, Sabine E
dc.contributor.authorLandberg, Rikard
dc.contributor.authorLinseisen, Jakob
dc.contributor.authorMattivi, Fulvio
dc.contributor.authorMensink, Ronald P
dc.contributor.authorScaccini, Cristina
dc.contributor.authorSkurk, Thomas
dc.contributor.authorTetens, Inge
dc.contributor.authorVergeres, Guy
dc.contributor.authorWishart, David S
dc.contributor.authorScalbert, Augustin
dc.contributor.authorFeskens, Edith J M
dc.date.accessioned2018-04-04T09:27:20Z
dc.date.available2018-04-04T09:27:20Z
dc.date.issued2017-11
dc.identifier.citationCombining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance. 2017, 76 (4):619-627 Proc Nutr Socen
dc.identifier.issn1475-2719
dc.identifier.pmid29137687
dc.identifier.doi10.1017/S0029665117003949
dc.identifier.urihttp://hdl.handle.net/10029/621744
dc.description.abstractFFQ, food diaries and 24 h recall methods represent the most commonly used dietary assessment tools in human studies on nutrition and health, but food intake biomarkers are assumed to provide a more objective reflection of intake. Unfortunately, very few of these biomarkers are sufficiently validated. This review provides an overview of food intake biomarker research and highlights present research efforts of the Joint Programming Initiative 'A Healthy Diet for a Healthy Life' (JPI-HDHL) Food Biomarkers Alliance (FoodBAll). In order to identify novel food intake biomarkers, the focus is on new food metabolomics techniques that allow the quantification of up to thousands of metabolites simultaneously, which may be applied in intervention and observational studies. As biomarkers are often influenced by various other factors than the food under investigation, FoodBAll developed a food intake biomarker quality and validity score aiming to assist the systematic evaluation of novel biomarkers. Moreover, to evaluate the applicability of nutritional biomarkers, studies are presently also focusing on associations between food intake biomarkers and diet-related disease risk. In order to be successful in these metabolomics studies, knowledge about available electronic metabolomics resources is necessary and further developments of these resources are essential. Ultimately, present efforts in this research area aim to advance quality control of traditional dietary assessment methods, advance compliance evaluation in nutritional intervention studies, and increase the significance of observational studies by investigating associations between nutrition and health.
dc.language.isoenen
dc.rightsinfo:eu-repo/semantics/closedAccessen
dc.titleCombining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance.en
dc.typeArticleen
dc.identifier.journalProc Nutr Soc 2017; 76(4):619-27en
html.description.abstractFFQ, food diaries and 24 h recall methods represent the most commonly used dietary assessment tools in human studies on nutrition and health, but food intake biomarkers are assumed to provide a more objective reflection of intake. Unfortunately, very few of these biomarkers are sufficiently validated. This review provides an overview of food intake biomarker research and highlights present research efforts of the Joint Programming Initiative 'A Healthy Diet for a Healthy Life' (JPI-HDHL) Food Biomarkers Alliance (FoodBAll). In order to identify novel food intake biomarkers, the focus is on new food metabolomics techniques that allow the quantification of up to thousands of metabolites simultaneously, which may be applied in intervention and observational studies. As biomarkers are often influenced by various other factors than the food under investigation, FoodBAll developed a food intake biomarker quality and validity score aiming to assist the systematic evaluation of novel biomarkers. Moreover, to evaluate the applicability of nutritional biomarkers, studies are presently also focusing on associations between food intake biomarkers and diet-related disease risk. In order to be successful in these metabolomics studies, knowledge about available electronic metabolomics resources is necessary and further developments of these resources are essential. Ultimately, present efforts in this research area aim to advance quality control of traditional dietary assessment methods, advance compliance evaluation in nutritional intervention studies, and increase the significance of observational studies by investigating associations between nutrition and health.


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