Clinical Characterization of Invasive Disease Caused by Haemophilus influenzae Serotype b in a High Vaccination Coverage Setting.

Monge, Susana; Mollema, Liesbeth; de Melker, Hester; Sanders, Elisabeth; van der Ende, Arie; Knol, Mirjam

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Authors

Monge, Susana
Mollema, Liesbeth
de Melker, Hester
Sanders, Elisabeth
van der Ende, Arie
Knol, Mirjam

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Article

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Title

Clinical Characterization of Invasive Disease Caused by Haemophilus influenzae Serotype b in a High Vaccination Coverage Setting.

Published in

J Pediatr Infect Dis Soc 2018; advance online publication (ahead of print)

Publiekssamenvatting

This national study characterized invasive Haemophilus influenzae serotype b infections. Vaccinated (n = 41) and nonvaccinated (n = 10) cases were similar regarding presentation as meningitis (68.8% vs 90.0%; P = .25), predisposing factors (29.3% vs 20.0%; P = .76), admission to intensive care unit or death (22.0% vs 10.0%; P = 1.00), or sequelae (21.6% vs 10.0%; P = .81). Haemophilus influenzae serotype b occurred in vaccinated, healthy children with comparable disease course.