No evidence found for an increased risk of long-term fatigue following human papillomavirus vaccination of adolescent girls.

Schurink-Van't Klooster, T M; Kemmeren, J M; van der Maas, N A T; van de Putte, E M; Ter Wolbeek, M; Nijhof, S L; Vanrolleghem, A M; van Vliet, J A; Sturkenboom, M; de Melker, H E

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Authors

Schurink-Van't Klooster, T M
Kemmeren, J M
van der Maas, N A T
van de Putte, E M
Ter Wolbeek, M
Nijhof, S L
Vanrolleghem, A M
van Vliet, J A
Sturkenboom, M
de Melker, H E

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Article

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Title

No evidence found for an increased risk of long-term fatigue following human papillomavirus vaccination of adolescent girls.

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Vaccine 2018; 36(45):6796-802

Publiekssamenvatting

In 2013, the Netherlands Pharmacovigilance Center Lareb published an overview of reports of long-lasting fatigue following bivalent HPV-vaccination (2vHPV). After an update of this overview in 2015, concerns regarding the safety of 2vHPV was picked up by the media, which led to further reports of long-lasting fatigue. Therefore, the Dutch National Institute for Public Health and the Environment (RIVM) investigated a possible association between HPV-vaccination and long-term fatigue.