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dc.contributor.authorPlachouras, Diamantis
dc.contributor.authorKärki, Tommi
dc.contributor.authorHansen, Sonja
dc.contributor.authorHopkins, Susan
dc.contributor.authorLyytikäinen, Outi
dc.contributor.authorMoro, Maria Luisa
dc.contributor.authorReilly, Jacqui
dc.contributor.authorZarb, Peter
dc.contributor.authorZingg, Walter
dc.contributor.authorKinross, Pete
dc.contributor.authorWeist, Klaus
dc.contributor.authorMonnet, Dominique L
dc.contributor.authorSuetens, Carl
dc.date.accessioned2019-03-22T12:45:36Z
dc.date.available2019-03-22T12:45:36Z
dc.date.issued2018-01-01
dc.identifier.issn1560-7917
dc.identifier.pmid30458917
dc.identifier.doi10.2807/1560-7917.ES.23.46.1800393
dc.identifier.urihttp://hdl.handle.net/10029/622944
dc.description.abstractAntimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms. In 2016-17, we performed the second point-prevalence survey (PPS) of healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals. We included 1,209 hospitals and 310,755 patients in 28 of 31 European Union/European Economic Area (EU/EEA) countries. The weighted prevalence of antimicrobial use in the EU/EEA was 30.5% (95% CI: 29.2-31.9%). The most common indication for prescribing antimicrobials was treatment of a community-acquired infection, followed by treatment of HAI and surgical prophylaxis. Over half (54.2%) of antimicrobials for surgical prophylaxis were prescribed for more than 1 day. The most common infections treated by antimicrobials were respiratory tract infections and the most commonly prescribed antimicrobial agents were penicillins with beta-lactamase inhibitors. There was wide variation of patients on antimicrobials, in the selection of antimicrobial agents and in antimicrobial stewardship resources and activities across the participating countries. The results of the PPS provide detailed information on antimicrobial use in European acute care hospitals, enable comparisons between countries and hospitals, and highlight key areas for national and European action that will support efforts towards prudent use of antimicrobials.en_US
dc.language.isoenen_US
dc.subjectantibiotic useen_US
dc.subjectantimicrobial useen_US
dc.subjecthealthcare-associated infectionsen_US
dc.subjecthospitalsen_US
dc.subjectpoint-prevalence surveyen_US
dc.subjectsurveillanceen_US
dc.titleAntimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017.en_US
dc.typeArticleen_US
dc.identifier.journalEuro Surveill 2018; 23(46):pii.1800393en_US
dc.source.journaltitleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin


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