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dc.contributor.authorVisser, Maartje
dc.contributor.authorVan der Ploeg, Catharina P B
dc.contributor.authorSmit, Colette
dc.contributor.authorHukkelhoven, Chantal W P M
dc.contributor.authorAbbink, Frithjofna
dc.contributor.authorvan Benthem, Birgit H B
dc.contributor.authorOp de Coul, Eline L M
dc.date.accessioned2019-04-08T07:30:42Z
dc.date.available2019-04-08T07:30:42Z
dc.date.issued2019-03-29
dc.identifier.issn1471-2458
dc.identifier.pmid30922277
dc.identifier.doi10.1186/s12889-019-6668-6
dc.identifier.urihttp://hdl.handle.net/10029/623002
dc.description.abstractIn 2014 the World Health Organisation (WHO) established validation criteria for elimination of mother-to-child transmission (EMTCT) of HIV and syphilis. Additionally, the WHO set targets to eliminate hepatitis, including hepatitis B (HBV). We evaluated to what extent the Netherlands has achieved the combined WHO criteria for EMTCT of HIV, syphilis and HBV. Data of HIV, syphilis and HBV infections among pregnant women and children (born in the Netherlands with congenital infection) for 2009-2015, and data required to validate the WHO criteria were collected from multiple sources: the antenatal screening registry, the HIV monitoring foundation database, the Perinatal Registry of the Netherlands, the national reference laboratory for congenital syphilis, and national HBV notification data. Screening coverage among pregnant women was > 99% for all years, and prevalence of HIV, syphilis and HBV was very low. In 2015, prevalence of HIV, syphilis and HBV was 0.06, 0.06 and 0.29%, respectively. No infections among children born in the Netherlands were reported in 2015 for all three diseases, and in previous years only sporadic cases were observed In 2015, treatment of HIV positive pregnant women was 100% and HBV vaccination of children from HBV positive mothers was > 99%. For syphilis, comprehensive data was lacking to validate WHO criteria. In the Netherlands, prevalence of maternal HIV, syphilis and HBV is low and congenital infections are extremely rare. All minimum WHO criteria for validation of EMTCT are met for HIV and HBV, but for syphilis more data are needed to prove elimination.en_US
dc.language.isoenen_US
dc.subjectAntenatal screeningen_US
dc.subjectCongenital syphilisen_US
dc.subjectHIVen_US
dc.subjectHepatitis Ben_US
dc.subjectPregnant womenen_US
dc.titleEvaluating progress towards triple elimination of mother-to-child transmission of HIV, syphilis and hepatitis B in the Netherlands.en_US
dc.typeArticleen_US
dc.identifier.journalBMC Public Health 2019; 19(1):353en_US
dc.source.journaltitleBMC public health


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