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dc.contributor.authorMughini-Gras, Lapo
dc.contributor.authorDorado-García, Alejandro
dc.contributor.authorvan Duijkeren, Engeline
dc.contributor.authorvan den Bunt, Gerrita
dc.contributor.authorDierikx, Cindy M
dc.contributor.authorBonten, Marc J M
dc.contributor.authorBootsma, Martin C J
dc.contributor.authorSchmitt, Heike
dc.contributor.authorHald, Tine
dc.contributor.authorEvers, Eric G
dc.contributor.authorde Koeijer, Aline
dc.contributor.authorvan Pelt, Wilfrid
dc.contributor.authorFranz, Eelco
dc.contributor.authorMevius, Dik J
dc.contributor.authorHeederik, Dick J J
dc.date.accessioned2019-10-21T19:39:26Z
dc.date.available2019-10-21T19:39:26Z
dc.date.issued2019-08-01
dc.identifier.issn2542-5196
dc.identifier.pmid31439317
dc.identifier.doi10.1016/S2542-5196(19)30130-5
dc.identifier.urihttp://hdl.handle.net/10029/623382
dc.description.abstractIn this population-based modelling study, we collected ESBL and pAmpC gene data on the Netherlands population for 2005-17 from published datasets of gene occurrences in E coli isolates from different sources, and from partners of the ESBL Attribution Consortium and the Dutch National Antimicrobial Surveillance System. Using these data, we applied an established source attribution model based on ESBL-EC and pAmpC-EC prevalence and gene data for humans, including high-risk populations (ie, returning travellers, clinical patients, farmers), farm and companion animals, food, surface freshwater, and wild birds, and human exposure data, to quantify the overall and gene-specific attributable sources of community-acquired ESBL-EC and pAmpC-EC intestinal carriage. We also used a simple transmission model to determine the basic reproduction number (R0) in the open community.en_US
dc.language.isoenen_US
dc.titleAttributable sources of community-acquired carriage of Escherichia coli containing β-lactam antibiotic resistance genes: a population-based modelling study.en_US
dc.typeArticleen_US
dc.identifier.journalLancet Planet Health 2019; 3(8):e357-e369en_US
dc.source.journaltitleThe Lancet. Planetary health


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