Transcatheter aortic valve replacement: clinical safety and performance data.
dc.contributor.author | van Baal, Jantine W P M | |
dc.contributor.author | Roszek, Boris | |
dc.contributor.author | van Elk, Merel | |
dc.contributor.author | Geertsma, Robert E | |
dc.date.accessioned | 2019-10-23T18:24:11Z | |
dc.date.available | 2019-10-23T18:24:11Z | |
dc.date.issued | 2019-10-01 | |
dc.identifier.issn | 1745-2422 | |
dc.identifier.pmid | 31564181 | |
dc.identifier.doi | 10.1080/17434440.2019.1674138 | |
dc.identifier.uri | http://hdl.handle.net/10029/623427 | |
dc.description.abstract | Introduction: Patients with severe aortic stenosis and regurgitation who are inoperable or at high-risk for surgery can be treated with transcatheter aortic valve replacement (TAVR). The aim of this study was to provide a comprehensive overview of the literature of TAVR and reported clinical and performance outcomes. Areas covered: A total of 16 devices, described in 204 articles describing clinical and performance outcomes, were included. The most frequently observed outcome was 30-day mortality, ranging between 0-23%. Other commonly reported clinical outcomes were 30-day stroke, ranging between 0-14.3% and pacemaker implantation, ranging from 0-44.9%. The most common valve performance outcome was aortic valve regurgitation, however, mostly reported at 7 days follow-up. Next to a follow-up period of 30 days, numerous articles reported outcomes at 6 months and 1 year. The numbers of articles describing outcomes with a longer follow-up as well as including intermediate and low-risk patients were limited. Expert commentary: This literature review provided a clear overview of the reported clinical and performance outcomes of TAVR devices. Despite the frequently used VARC-2 definitions, we identified a huge variation across studies. Future studies using standardized definitions of study set-ups and outcomes are essential and might lead to better insights of TAVR. | en_US |
dc.language.iso | en | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | Transcatheter aortic valve implantation (TAVI) | en_US |
dc.subject | VARC | en_US |
dc.subject | clinical data | en_US |
dc.subject | transcatheter aortic valve replacement (TAVR) | en_US |
dc.subject | transcatheter heart valve (THV) | en_US |
dc.title | Transcatheter aortic valve replacement: clinical safety and performance data. | en_US |
dc.type | Article | en_US |
dc.identifier.journal | Expert Rev Med Devices 2019; 16(10):899-911 | en_US |
dc.source.journaltitle | Expert review of medical devices |