Show simple item record

dc.contributor.authorStreng, Astrid A
dc.contributor.authorLoef, Bette
dc.contributor.authorDollé, Martijn E T
dc.contributor.authorvan der Horst, Gijsbertus T J
dc.contributor.authorChaves, Inês
dc.contributor.authorProper, Karin I
dc.contributor.authorvan Kerkhof, Linda W M
dc.date.accessioned2022-02-15T08:12:52Z
dc.date.available2022-02-15T08:12:52Z
dc.date.issued2022-02-07
dc.identifier.pmid35132155
dc.identifier.doi10.1038/s41598-022-06122-w
dc.identifier.urihttp://hdl.handle.net/10029/625564
dc.description.abstractNight shift work is associated with increased health risks. Here we examined the association of metabolic risk factors and immune cell counts, with both night shift work and particular characteristics thereof: frequency, duration and consecutive night shifts. We performed a cross-sectional study using data from 10,201 non-shift workers and 1062 night shift workers of the Lifelines Cohort study. Linear regression analyses, adjusted for demographic, lifestyle and occupational factors, were used to study associations of night shift work characteristics with metabolic risk factors and immune cell counts. Night shift workers had an increased BMI, waist circumference and immune cell counts compared to non-shift workers. This was especially seen in night shift workers who had a higher frequency of night shifts per month (≥ 5: BMI: B = 0.81 kg/m2 (95%-CI = 0.43-1.10); waist circumference: B = 1.58 cm (95%-Cl = 0.34-1.71; leukocytes: B = 0.19 × 109 cells/L (95%-CI = 0.04-0.34 × 109)) and worked more consecutive night shifts (> 3: BMI: B = 0.92 kg/m2 (95%-CI = 0.41-1.43); waist circumference: B = 1.85 cm (95%-Cl = 0.45-3.24); leukocytes: B = 0.32 × 109 cells/L (95%-CI = 0.09-0.55 × 109)). This association was less pronounced in long-term night shift workers (≥ 20 years). Our findings provide evidence for the association between night shift work characteristics and BMI, waist circumference and leukocytes (including, monocytes, lymphocytes, and basophil granulocytes).en_US
dc.language.isoenen_US
dc.rights© 2022. The Author(s).
dc.titleNight shift work characteristics are associated with several elevated metabolic risk factors and immune cell counts in a cross-sectional study.en_US
dc.typeArticleen_US
dc.identifier.eissn2045-2322
dc.identifier.journalScientific reports 2022;12(1):2022en_US
dc.source.journaltitleScientific reports
dc.source.volume12
dc.source.issue1
dc.source.beginpage2022
dc.source.endpage
dc.source.countryUnited Kingdom
dc.source.countryUnited Kingdom
dc.source.countryUnited Kingdom
dc.source.countryEngland


This item appears in the following Collection(s)

Show simple item record