Using data on social contacts to estimate age-specific transmission parameters for respiratory-spread infectious agents.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
TitleUsing data on social contacts to estimate age-specific transmission parameters for respiratory-spread infectious agents.
PubliekssamenvattingThe estimation of transmission parameters has been problematic for diseases that rely predominantly on transmission of pathogens from person to person through small infectious droplets. Age-specific transmission parameters determine how such respiratory agents will spread among different age groups in a human population. Estimating the values of these parameters is essential in planning an effective response to potentially devastating pandemics of smallpox or influenza and in designing control strategies for diseases such as measles or mumps. In this study, the authors estimated age-specific transmission parameters by augmenting infectious disease data with auxiliary data on self-reported numbers of conversational partners per person. They show that models that use transmission parameters based on these self-reported social contacts are better able to capture the observed patterns of infection of endemically circulating mumps, as well as observed patterns of spread of pandemic influenza. The estimated age-specific transmission parameters suggested that school-aged children and young adults will experience the highest incidence of infection and will contribute most to further spread of infections during the initial phase of an emerging respiratory-spread epidemic in a completely susceptible population. These findings have important implications for controlling future outbreaks of novel respiratory-spread infectious agents.
- Invited commentary: Challenges of using contact data to understand acute respiratory disease transmission.
- Authors: Halloran ME
- Issue date: 2006 Nov 15
- A Bayesian MCMC approach to study transmission of influenza: application to household longitudinal data.
- Authors: Cauchemez S, Carrat F, Viboud C, Valleron AJ, Boëlle PY
- Issue date: 2004 Nov 30
- Social contacts of school children and the transmission of respiratory-spread pathogens.
- Authors: Mikolajczyk RT, Akmatov MK, Rastin S, Kretzschmar M
- Issue date: 2008 Jun
- [Epidemic of respiratory tract infections by Mycoplasma pneumoniae in an institute for mentally disabled, investigated with polymerase chain reaction of a throat swab specimen].
- Authors: Dorigo-Zetsma JW, de Wit M, Szabó JS, Schneeberger PM
- Issue date: 1999 Jun 12
- Illness transmission in the home: a possible role for alcohol-based hand gels.
- Authors: Lee GM, Salomon JA, Friedman JF, Hibberd PL, Ross-Degnan D, Zasloff E, Bediako S, Goldmann DA
- Issue date: 2005 Apr