van Beek, Jankode Graaf, MirandaSmits, SaskiaSchapendonk, Claudia M EVerjans, Georges M G MVennema, Harryvan der Eijk, Annemiek APhan, My V TCotten, MatthewKoopmans, Marion2018-03-222018-03-222017-12-19Whole-Genome Next-Generation Sequencing to Study Within-Host Evolution of Norovirus (NoV) Among Immunocompromised Patients With Chronic NoV Infection. 2017, 216 (12):1513-1524 J. Infect. Dis.1537-66132902911510.1093/infdis/jix520http://hdl.handle.net/10029/621695The genus Norovirus comprises large genetic diversity, and new GII.4 variants emerge every 2-3 years. It is unknown in which host these new variants originate. Here we study whether prolonged shedders within the immunocompromised population could be a reservoir for newly emerging strains.eninfo:eu-repo/semantics/closedAccessWhole-Genome Next-Generation Sequencing to Study Within-Host Evolution of Norovirus (NoV) Among Immunocompromised Patients With Chronic NoV Infection.ArticleJ Infect Dis 2017; 216(12):1513-24