Baunwall, Simon Mark DahlTerveer, Elisabeth MDahlerup, Jens FrederikErikstrup, ChristianArkkila, PerttuVehreschild, Maria JgtIaniro, GianlucaGasbarrini, AntonioSokol, HarryKump, Patrizia KSatokari, ReettaDe Looze, DannyVermeire, SéverineNakov, RadislavBrezina, JanHelms, MortenKjeldsen, JensRode, Anne AKousgaard, Sabrina JustAlric, LaurentTrang-Poisson, CarolineScanzi, JulienLink, AlexanderStallmach, AndreasKupcinskas, JuozasJohnsen, Peter HolgerGarborg, KjetilRodríguez, Eugenia SánchezSerrander, LenaBrummer, Robert JGalpérine, Katerina TatianaGoldenberg, Simon DMullish, Benjamin HWilliams, Horace RtIqbal, Tariq HPonsioen, CyrielKuijper, Ed JCammarota, GiovanniKeller, Josbert JHvas, Christian Lodberg2021-12-232021-12-232021-07-193469338810.1016/j.lanepe.2021.100181http://hdl.handle.net/10029/625464In 2019, 31 FMT centres from 17 countries reported a total of 1,874 (median 25, quartile 10-64) FMT procedures; 1,077 (57%) with Clostridioides difficile infection (CDI) as indication, 791 (42%) with experimental indications, and 6 (0•3%) unaccounted for. Adjusted to population size, 0•257 per 100,000 population received FMT for CDI and 0•189 per 100,000 population for experimental indications. With estimated 12,400 (6,100-28,500) annual cases of multiple, recurrent CDI and indication for FMT in Europe, the current European FMT activity covers approximately 10% of the patients with indication. The participating centres demonstrated high safety standards and adherence to international consensus guidelines. Formal or informal regulation from health authorities was present at 21 (68%) centres.en© 2021 The Authors.Abbreviations: CDI, Clostridioides difficile infectionClostridioides difficileECDC, European Centre for Disease Prevention and ControlFMTFMT, Faecal microbiota transplantationFaecal microbiota transplantationIQR, Interquartile rangeREDCap, Research Data Capture softwareSARS-CoV-2, Severe acute respiratory syndrome coronavirus 2Stool bankingUEG, United Gastroenterology EuropeanArticle2666-7762Lancet Reg Health Eur 2021; 19;9:100181