Gelderloos, Anne TLakerveld, Anke JSchepp, Rutger MNicolaie, Mioara Alinavan Beek, JosineBeckers, Lisavan Binnendijk, Robert SRots, Nynke Yvan Kasteren, Puck B2024-08-052024-08-052024-07-262050-00683907110910.1002/cti2.1521http://hdl.handle.net/10029/627761Here, we assessed the development of spike S1-specific serum antibody-dependent cellular phagocytosis (ADCP), complement deposition (ADCD) and natural killer cell activation (ADNKA), alongside specific antibody binding concentrations (IgG, IgA and IgM) and IgG avidity in healthy adults (n = 38, 18-56 years) and children (n = 21, 5-16 years) following primary SARS-CoV-2 infection, with a 10-month longitudinal follow-up. Differences between groups were assessed using a nonparametric Kruskal-Wallis test with Dunn's multiple comparisons test.en© 2024 The Author(s). Clinical & Translational Immunology published by John Wiley & Sons Australia, Ltd on behalf of Australian and New Zealand Society for Immunology, Inc.Fc‐functionalityadultschildrenmonocytesnatural killer cellsviral infectionPrimary SARS-CoV-2 infection in children and adults results in similar Fc-mediated antibody effector function patternsArticleClin Transl Immunol 2024; 13(8):e1521