An adverse outcome pathway on the disruption of retinoic acid metabolism leading to developmental craniofacial defects.

Menegola, ElenaVeltman, Christina H JBattistoni, MariaDi Renzo, FrancescaMoretto, AngeloMetruccio, FrancescaBeronius, AnnaZilliacus, JohannaKyriakopoulou, KaterinaSpyropoulou, AnastasiaMachera, Kyriakivan der Ven, Leo T MLuijten, Mirjam2021-07-152021-07-152021-06-263418616610.1016/j.tox.2021.152843http://hdl.handle.net/10029/625074enCopyright © 2021 Elsevier B.V. All rights reserved.AOPConazolesCraniofacial defectsCyp 26 inhibitionRetinoic acidAn adverse outcome pathway on the disruption of retinoic acid metabolism leading to developmental craniofacial defects.Article1879-3185Toxicology 2021; 458:152843