Effectiveness of analgesic ear drops as add-on treatment to oral analgesics in children with acute otitis media: study protocol of the OPTIMA pragmatic randomised controlled trial.

de Sévaux, Joline L HDamoiseaux, Roger A M JHullegie, SaskiaSanders, Elisabeth A Mde Wit, G ArdineZuithoff, Nicolaas P AYardley, LucyAnthierens, SibylLittle, PaulHay, Alastair DSchilder, Anne G MVenekamp, Roderick P2023-02-282023-02-282023-02-223681350410.1136/bmjopen-2022-062071http://hdl.handle.net/10029/626489en© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.EpidemiologyPAIN MANAGEMENTPRIMARY CAREPaediatric infectious disease & immunisationPaediatric otolaryngologyQUALITATIVE RESEARCHEffectiveness of analgesic ear drops as add-on treatment to oral analgesics in children with acute otitis media: study protocol of the OPTIMA pragmatic randomised controlled trial.Article2044-6055BMJ Open 2023;13(2):e062071