Maternal measles antibodies and their influence on all-cause mortality following measles vaccination: an alternative to measure very low maternal antibody levels.

Smits, GabyStabell Benn, ChristineWhittle, Hiltonvan Binnendijk, RobAaby, Petervan der Klis, Fiona2018-11-202018-11-202018-10-16Maternal measles antibodies and their influence on all-cause mortality following measles vaccination: an alternative to measure very low maternal antibody levels. 2018 Clin. Infect. Dis.1537-65913032903010.1093/cid/ciy900http://hdl.handle.net/10029/622291It was previously shown by hemagglutination inhibition that measles-vaccination in the presence of maternal measles antibodies was associated with reduced all-cause mortality. We confirmed this serological association using a multiplexed immunoassay as a sensitive alternative and estimated a threshold concentration (28.7 mIU/ml), that correlates with lower all-cause mortality (p=0.02).eninfo:eu-repo/semantics/closedAccessMaternal measles antibodies and their influence on all-cause mortality following measles vaccination: an alternative to measure very low maternal antibody levels.Clin Infect Dis 2019; 68(10):1758-60