van der Heiden, MariekeDuizendstra, AafkeBerbers, Guy AMBoots, Annemieke MHBuisman, Anne-Marie2018-01-092018-01-092017-10-09Tetanus Toxoid carrier protein induced T-helper cell responses upon vaccination of middle-aged adults. 2017, 35 (42):5581-5588 Vaccine1873-25182888244410.1016/j.vaccine.2017.08.056http://hdl.handle.net/10029/621103Vaccines frequently induce suboptimal immune responses in the elderly, due to immunological ageing. Timely vaccination may be a strategy to overcome this problem, which classifies middle-aged adults asan interesting target group for future vaccine interventions. However, the immunological fitness of the middle-aged population is ill-defined. It is currently unknown whether effective T-cell help towards B-cells is initiated by conjugate-carrier vaccines at middle-age.enArchived with thanks to VaccineTetanus Toxoid carrier protein induced T-helper cell responses upon vaccination of middle-aged adultsArticleVaccine 2017, 35(42):5581-8