Rotee, I L MOng, D S YKoeleman, J G MVos, E R ATramper-Stranders, G A2022-03-142022-03-142021-10-093526202610.1016/j.jcvp.2021.100045http://hdl.handle.net/10029/625612A total of 209 samples in period 1 and 240 samples in period 2 were collected (median age 7.1 years, IQR 1.5-13.5). SARS-CoV-2 antibodies were detected in 4.1% and 13.8%, respectively (p< 0.001). Seroprevalence was higher compared to national paediatric data, but did not differ with regional estimates. Most children with SARS-CoV-2 antibodies were seen in the outpatient clinic for general paediatric problems with no differences in medical reasons for presentation between the two periods.en© 2021 The Authors.COVID-19General paediatric patientsSARS-CoV-2Serologypopulation studyTrends in SARS-CoV-2 seroprevalence amongst urban paediatric patients compared with a nationwide cohort in the Netherlands.Article2667-0380Journal of clinical virology plus 2022;1(4):100045