Initiation of anti-retroviral therapy before pregnancy reduces the risk of infection-related hospitalization in HIV-exposed uninfected infants born in a high-income country.

Goetghebuer, TessaSmolen, Kinga KAdler, CatherineDas, JishnuMcBride, TrevorSmits, GabyLecomte, SandraHaelterman, EdwigeBarlow, PatriciaPiedra, Pedro Avan der Klis, FionaKollmann, Tobias RLauffenburger, Douglas AAlter, GalitLevy, JackMarchant, Arnaud2018-10-152018-10-152018-09-12Initiation of anti-retroviral therapy before pregnancy reduces the risk of infection-related hospitalization in HIV-exposed uninfected infants born in a high-income country. 2018 Clin. Infect. Dis.1537-65913021568910.1093/cid/ciy673http://hdl.handle.net/10029/622192Epidemiological studies conducted in low and high-income countries showed that infants exposed to maternal HIV but not infected themselves by the virus have a high risk of severe infections. Immune alterations during fetal life have been proposed as a possible mechanism.eninfo:eu-repo/semantics/closedAccessInitiation of anti-retroviral therapy before pregnancy reduces the risk of infection-related hospitalization in HIV-exposed uninfected infants born in a high-income country.ArticleClin Infect Dis 2019; 68(7):1193-203