Alterations to the urinary metabolome following semi-controlled short exposures to ultrafine particles at a major airport.

Selley, LizaLammers, ArianaLe Guennec, AdrienPirhadi, MiladSioutas, ConstantinosJanssen, NicoleMaitland-van der Zee, Anke HMudway, IanCassee, Flemming2021-09-212021-09-212021-09-103451715910.1016/j.ijheh.2021.113803http://hdl.handle.net/10029/62526721 healthy, non-smoking volunteers (aged 19-27 years) were repeatedly (2-5 visits) exposed for 5h to ambient air at Amsterdam Airport Schiphol, while performing intermittent, moderate exercise. Pre- to-post exposure changes in urinary metabolite concentrations were assessed via 1H NMR spectroscopy and related to total and source-specific particle number concentrations (PNC) using linear mixed effects models.enCopyright © 2021 The Authors. Published by Elsevier GmbH.. All rights reserved.AirportBiomarkersHuman exposureMetabolomeOxidative stressUltrafine particlesAlterations to the urinary metabolome following semi-controlled short exposures to ultrafine particles at a major airport.Article1618-131XInt J Hyg Environ Health 2021; 237:113803 advance online publication (ahead of print)