Leopold, AnnegaaikeBloor, MichelleGroh, KseniaPosthuma, LeoSanderson, HansSchreiber, HannaSchür, ChristophThomas, Paul2025-07-192025-07-192025-07-011551-37934039711010.1093/inteam/vjaf059https://rivm.openrepository.com/handle/10029/655503enResearch gaps and recommendations to improve the Safe and Sustainable by Design framework.Journal ArticleIntegr Environ Assess Manag 2025; 21(4):735-7388139937