Impact of in vitro experimental variation in kinetic parameters on physiologically based kinetic (PBK) model simulations.

Punt, AnsBos, PeterHakkert, BettyLouisse, Jochem2022-08-012022-08-012022-07-223590149610.14573/altex.2202131http://hdl.handle.net/10029/625974enapparent permeability fractionin vitro kinetics clearancephysiologically based kinetic (PBK) modelingunbound plasmaImpact of in vitro experimental variation in kinetic parameters on physiologically based kinetic (PBK) model simulations.Article1868-8551ALTEX 2023; 40(2):237-247