van der Lee, SaskiaSanders, Elisabeth A MBerbers, Guy A MBuisman, Anne-Marie2018-04-052018-04-052018Whole-cell or acellular pertussis vaccination in infancy determines IgG subclass profiles to DTaP booster vaccination. 2018, 36 (2):220-226 Vaccine1873-25182919904110.1016/j.vaccine.2017.11.066http://hdl.handle.net/10029/621758Duration of protection against pertussis is shorter in adolescents who have been immunized with acellular pertussis (aP) in infancy compared with adolescents who received whole-cell pertussis (wP) vaccines in infancy, which is related to immune responses elicited by these priming vaccines. To better understand differences in vaccine induced immunity, we determined pertussis, diphtheria, and tetanus (DTaP) vaccine antigen-specific IgG subclass responses in wP- and aP-primed children before and after two successive DTaP booster vaccinations.eninfo:eu-repo/semantics/closedAccessWhole-cell or acellular pertussis vaccination in infancy determines IgG subclass profiles to DTaP booster vaccination.ArticleVaccine 2018; 36(2):220-6