Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Responses from a survey of National Control Laboratories and National Regulatory Authorities.

Lilley, ElliotBruysters, MartijnDas, PradipGill, SimeonIsbrucker, RichardJones, DavidHolmes, Anthony2023-11-152023-11-152023-11-013792262510.1016/j.biologicals.2023.101721http://hdl.handle.net/10029/627062enCopyright © 2023. Published by Elsevier Ltd.3RsBatch release testingBiological therapeuticsNC3RsNational Control LaboratoriesNational Regulatory AuthoritiesNon-animal testing strategiesQuality controlSurveyVaccine manufacturersVaccinesWHOIntegrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Responses from a survey of National Control Laboratories and National Regulatory Authorities.Article1095-8320Biologicals 2023;84:101721