Major principles and concepts of risk assessment
Brambilla, Gianfranco Greiner, Matthias Gundert-Remy, Ursula Heinemeyer, Gerhard Neisel, Friederike ter Burg, Wouter
Brambilla, Gianfranco
Greiner, Matthias
Gundert-Remy, Ursula
Heinemeyer, Gerhard
Neisel, Friederike
ter Burg, Wouter
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Open Access
Type
Book chapter
Language
en
Date of publication
2020-06-02
Year of publication
Research Projects
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Journal Issue
Title
Major principles and concepts of risk assessment
Translated Title
Published in
In: G Heinemeyer, M Jantunen, P Hakkinen (eds.). The practice of consumer exposure assessment. - 2020; pp. 5-54
Abstract
Risk has two components: a known threat, which in the context of toxicology is called a hazard, and an exposure situation. In toxicology, risk assessment requires quantification of the two components: (1) the hazard which is the possible health impairment, given by the inherent toxicological and physicochemical properties of a substance. This is called hazard identification, and combined with dose-response characterisation it becomes, hazard assessment, and (2) the exposure which has to be assessed and quantified. The ratio of hazard assessment and exposure assessment is the probability that under a given exposure situation, a specified health impairment will materialise.
Description
Publisher
Cham : Springer, 2020