The use of Faecal Microbiota Transplantation (FMT) in Europe: A Europe-wide survey.
Baunwall, Simon Mark Dahl; Terveer, Elisabeth M; Dahlerup, Jens Frederik; Erikstrup, Christian; Arkkila, Perttu; Vehreschild, Maria Jgt; Ianiro, Gianluca; Gasbarrini, Antonio; Sokol, Harry; Kump, Patrizia K; Satokari, Reetta; De Looze, Danny; Vermeire, Séverine; Nakov, Radislav; Brezina, Jan; Helms, Morten; Kjeldsen, Jens; Rode, Anne A; Kousgaard, Sabrina Just; Alric, Laurent; Trang-Poisson, Caroline; Scanzi, Julien; Link, Alexander; Stallmach, Andreas; Kupcinskas, Juozas; Johnsen, Peter Holger; Garborg, Kjetil; Rodríguez, Eugenia Sánchez; Serrander, Lena; Brummer, Robert J; Galpérine, Katerina Tatiana; Goldenberg, Simon D; Mullish, Benjamin H; Williams, Horace Rt; Iqbal, Tariq H; Ponsioen, Cyriel; Kuijper, Ed J; Cammarota, Giovanni; Keller, Josbert J; Hvas, Christian Lodberg
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Open Access
Type
Article
Language
en
Date
2021-07-19
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Title
The use of Faecal Microbiota Transplantation (FMT) in Europe: A Europe-wide survey.
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Lancet Reg Health Eur 2021; 19;9:100181
Abstract
In 2019, 31 FMT centres from 17 countries reported a total of 1,874 (median 25, quartile 10-64) FMT procedures; 1,077 (57%) with Clostridioides difficile infection (CDI) as indication, 791 (42%) with experimental indications, and 6 (0•3%) unaccounted for. Adjusted to population size, 0•257 per 100,000 population received FMT for CDI and 0•189 per 100,000 population for experimental indications. With estimated 12,400 (6,100-28,500) annual cases of multiple, recurrent CDI and indication for FMT in Europe, the current European FMT activity covers approximately 10% of the patients with indication. The participating centres demonstrated high safety standards and adherence to international consensus guidelines. Formal or informal regulation from health authorities was present at 21 (68%) centres.