Rethinking developmental toxicity testing: Evolution or revolution?
Scialli, Anthony R Daston, George Chen, Connie Coder, Prägati S Euling, Susan Y Foreman, Jennifer Hoberman, Alan M Hui, Julia Knudsen, Thomas Makris, Susan L
Scialli, Anthony R
Daston, George
Chen, Connie
Coder, Prägati S
Euling, Susan Y
Foreman, Jennifer
Hoberman, Alan M
Hui, Julia
Knudsen, Thomas
Makris, Susan L
Citations
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Series / Report no.
Open Access
Type
Article
Language
en
Date of publication
2018-02-12
Year of publication
Research Projects
Organizational Units
Journal Issue
Title
Rethinking developmental toxicity testing: Evolution or revolution?
Translated Title
Published in
Birth Defects Res 2018; advance online publication (ahead of print)
Abstract
Current developmental toxicity testing adheres largely to protocols suggested in 1966 involving the administration of test compound to pregnant laboratory animals. After more than 50 years of embryo-fetal development testing, are we ready to consider a different approach to human developmental toxicity testing?