Rethinking developmental toxicity testing: Evolution or revolution?
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Open Access
Type
Article
Language
en
Date
2018-02-12
Research Projects
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Journal Issue
Title
Rethinking developmental toxicity testing: Evolution or revolution?
Translated Title
Published in
Birth Defects Res 2018; advance online publication (ahead of print)
Abstract
Current developmental toxicity testing adheres largely to protocols suggested in 1966 involving the administration of test compound to pregnant laboratory animals. After more than 50 years of embryo-fetal development testing, are we ready to consider a different approach to human developmental toxicity testing?