Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Zamora-Ros, Raul Alghamdi, Muath A Cayssials, Valerie Franceschi, Silvia Almquist, Martin Hennings, Joakim Sandström, Maria Tsilidis, Konstantinos K Weiderpass, Elisabete Boutron-Ruault, Marie-Christine
Zamora-Ros, Raul
Alghamdi, Muath A
Cayssials, Valerie
Franceschi, Silvia
Almquist, Martin
Hennings, Joakim
Sandström, Maria
Tsilidis, Konstantinos K
Weiderpass, Elisabete
Boutron-Ruault, Marie-Christine
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Open Access
Type
Article
Language
en
Date of publication
2018-12-10
Year of publication
Research Projects
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Journal Issue
Title
Coffee and tea drinking in relation to the risk of differentiated thyroid carcinoma: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Translated Title
Published in
Eur J Nutr 2019; 58(8):3303-12
Abstract
Coffee and tea constituents have shown several anti-carcinogenic activities in cellular and animal studies, including against thyroid cancer (TC). However, epidemiological evidence is still limited and inconsistent. Therefore, we aimed to investigate this association in a large prospective study. The study was conducted in the EPIC (European Prospective Investigation into Cancer and Nutrition) cohort, which included 476,108 adult men and women. Coffee and tea intakes were assessed through validated country-specific dietary questionnaires. During a mean follow-up of 14 years, 748 first incident differentiated TC cases (including 601 papillary and 109 follicular TC) were identified. Coffee consumption (per 100 mL/day) was not associated either with total differentiated TC risk (HR In this large prospective study, coffee and tea consumptions were not associated with TC risk.