KIM-1 as a Blood-Based Marker for Early Detection of Kidney Cancer: A Prospective Nested Case-Control Study.
Scelo, Ghislaine; Muller, David C; Riboli, Elio; Johansson, Mattias; Cross, Amanda J; Vineis, Paolo; Tsilidis, Konstantinos K; Brennan, Paul; Boeing, Heiner; Peeters, Petra H M; Vermeulen, Roel C H; Overvad, Kim; Bueno-de-Mesquita, H Bas; Severi, Gianluca; Perduca, Vittorio; Kvaskoff, Marina; Trichopoulou, Antonia; la Vecchia, Carlo; Karakatsani, Anna; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Weiderpass, Elisabete; Sandanger, Torkjel M; Nøst, Therese H; Agudo, Antonio; Quirós, J Ramón; Rodríguez-Barranco, Miguel; Chirlaque, Maria-Dolores; Key, Timothy J; Khanna, Prateek; Bonventre, Joseph V; Sabbisetti, Venkata S; Bhatt, Rupal S
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Open Access
Type
Article
Language
en
Date
2018-11-15
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Title
KIM-1 as a Blood-Based Marker for Early Detection of Kidney Cancer: A Prospective Nested Case-Control Study.
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Published in
Clin Cancer Res 2018; 24(22):5594-5601
Abstract
Renal cell carcinoma (RCC) has the potential for cure with surgery when diagnosed at an early stage. Kidney injury molecule-1 (KIM-1) has been shown to be elevated in the plasma of RCC patients. We aimed to test whether plasma KIM-1 could represent a means of detecting RCC prior to clinical diagnosis.