Influence of demographic changes on the impact of vaccination against varicella and herpes zoster in Germany - a mathematical modelling study.

Horn, Johannes; Damm, Oliver; Greiner, Wolfgang; Hengel, Hartmut; Kretzschmar, Mirjam E; Siedler, Anette; Ultsch, Bernhard; Weidemann, Felix; Wichmann, Ole; Karch, André; Mikolajczyk, Rafael T

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Authors

Horn, Johannes
Damm, Oliver
Greiner, Wolfgang
Hengel, Hartmut
Kretzschmar, Mirjam E
Siedler, Anette
Ultsch, Bernhard
Weidemann, Felix
Wichmann, Ole
Karch, AndréMikolajczyk, Rafael T

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Title

Influence of demographic changes on the impact of vaccination against varicella and herpes zoster in Germany - a mathematical modelling study.

Published in

BMC Med 2018; 16(1):3

Publiekssamenvatting

Epidemiological studies suggest that reduced exposure to varicella might lead to an increased risk for herpes zoster (HZ). Reduction of exposure to varicella is a consequence of varicella vaccination but also of demographic changes. We analyzed how the combination of vaccination programs and demographic dynamics will affect the epidemiology of varicella and HZ in Germany over the next 50 years.