Large-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis.

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dc.contributor.authorRuesen, Carolien
dc.contributor.authorChaidir, Lidya
dc.contributor.authorvan Laarhoven, Arjan
dc.contributor.authorDian, Sofiati
dc.contributor.authorGaniem, Ahmad Rizal
dc.contributor.authorNebenzahl-Guimaraes, Hanna
dc.contributor.authorHuynen, Martijn A
dc.contributor.authorAlisjahbana, Bachti
dc.contributor.authorDutilh, Bas E
dc.contributor.authorvan Crevel, Reinout
dc.date.accessioned2018-02-12T12:55:47Z
dc.date.available2018-02-12T12:55:47Z
dc.date.issued2018
dc.description.abstractMeningitis is the most severe manifestation of tuberculosis. It is largely unknown why some people develop pulmonary TB (PTB) and others TB meningitis (TBM); we examined if the genetic background of infecting M. tuberculosis strains may be relevant.
dc.identifier.citationLarge-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis. 2018, 19 (1):122 BMC Genomicsen
dc.identifier.doi10.1186/s12864-018-4498-z
dc.identifier.issn1471-2164
dc.identifier.journalBMC Genomics 2018; 19(1):122en
dc.identifier.pmid29402222
dc.identifier.urihttp://hdl.handle.net/10029/621405
dc.language.isoenen
dc.rightsArchived with thanks to BMC genomicsen
dc.titleLarge-scale genomic analysis shows association between homoplastic genetic variation in Mycobacterium tuberculosis genes and meningeal or pulmonary tuberculosis.en
dc.typeArticleen
dspace.entity.typePublication
html.description.abstractMeningitis is the most severe manifestation of tuberculosis. It is largely unknown why some people develop pulmonary TB (PTB) and others TB meningitis (TBM); we examined if the genetic background of infecting M. tuberculosis strains may be relevant.
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